We conclude that NIR PBM combined with CoQ10 had multiple mechanisms of action, targeting mitochondrial bioenergetics and biogenesis as well as anti-neuroinflammation in this model of ischemic brain damage in AA animals. The present study suggests that the PBM and CoQ10 treatments, alone or in combination, have procognitive effect in ischemic damage to aged brains of mice.
OPEN FILEConclusion—The NEST-1 study indicates that infrared laser therapy has shown initial safety and effectiveness for the treatment of ischemic stroke in humans when initiated within 24 hours of stroke onset. A larger confirmatory trial to demonstrate safety and effectiveness is warranted.
OPEN FILEConclusion: Our data showed that both treatments can be used to treat chronic migraine, without notable differences between them.
OPEN FILEConclusion: Our results demonstrated that NIR TPBM had an anti-anxiety and anti-depressive effect in CRS mice, which is probably linked to increasing 5-HT and decreasing NO levels in the PFC and Hipp areas. Also, the maximum anti-anxiety and anti-depressive effect was produced at dose of 8 J/cm2.
OPEN FILEAltogether, in these three cases, t-PBM showed encouraging results as an intervention for DS with seemingly few or no side effects or adverse events.
OPEN FILEAll patients reported a marked reduction of anhedonia/apathy and increase of libido, together with isolated improvements in anxiety, sleep, irritability, and impulsivity.
OPEN FILEConclusions: In summary, our early observations are the first to note the impact of PBM on patients’ signs and symptoms over an extended period, up to 24 months, and lays the groundwork for further development to clinical trial.
OPEN FILEWe highlight the idea that photobiomodulation may form an ideal treatment option for autism, one that is certainly worthy of further investigation.
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