Photobiomodulation of Dental Derived Mesenchymal Stem Cells: A Systematic Review

Conclusions: PBMtherapy has no deleterious effects on ddMSCs. Although no other clear conclusion was obtained because of the scarce number of publications, the results of these studies are pointing to an important tendency of PBM therapy to improve ddMSCs’ viability and proliferation.

Regenerative Medicine, Stem Cells, and Low-Level Laser Therapy: Future Directives

The idea of being able to replace, restore, or regenerate damaged or diseased tissues and organs in order to establish normal function in the human body has never been so prominent and possible than with the development of the field of regenerative medicine.

Photobiomodulation Therapy: Communicating with Stem Cells for Regeneration

The major purpose of this special issue is to provide a collated overview of the progress and increasing excitement for the use of PBM therapy with stem cells for regenerative applications.

Effect of platelet-rich plasma, low-level laser therapy (650 nm) or their combination on the healing of Achilles tendon in rabbits: a histopathological study

Furthermore, it was found that the combined treatment with PRP and LLLT is even more efficient than when each of the two treatments is used alone but there was no significant difference (P>0.05) between the two groups of laser and PRP. However, the treatments combining PRP and LLLT showed significant results (P<0.05). Our results demonstrate a decrease in the time of tendon regeneration by using the two therapies combined, accelerating the healing process.

Low-level laser irradiation induces in vitro proliferation of mesenchymal stem cells

Conclusion: Low-level laser irradiation stimulated the proliferation of mouse mesenchymal stem cells without causing nuclear alterations. The biostimulation of mesenchymal stem cells using laser therapy might be an important tool for regenerative therapy and tissue engineering.

Effect of Photobiomodulation Therapy on the Increase of Viability and Proliferation of Human Mesenchymal Stem Cells

Conclusions: Irradiation with the MLS M1 system can be used in vitro to modulate MSCs in preparation for therapeutic applications. This will assist in designing further studies to optimize the radiation parameters and elucidate the molecular mechanisms of action of the radiation.

Effects of LLLT on Stem Cells form the Heart and Bone Marrow

Synergistic effects of low-level laser and mesenchymal stem cells on functional recovery in rats with crushed sciatic nerves

MSC transplantation combined with LLLT could achieve better results in functional recovery than a conventional treatment of MSC or LLLT alone. LLLT has a synergistic effect in providing greater functional recovery with MSC transplantation after nerve crush injury.

Differentiation Potential of Adipose-Derived Stem Cells When Cocultured with Smooth Muscle Cells, and the Role of Low-Intensity Laser Irradiation

Conclusions: These results suggest that ADSCs have the ability to differentiate into SMCs when cocultured with SMCs, whereas LILI potentially augments the differentiation potential and need. This further highlights the significant role that LILI has to offer ADSC therapy in regenerative medicine.

Effect of Photobiomodulation on Mesenchymal Stem Cells

Conclusions: PBM has positive effects on MSCs. This review concluded that doses of 0.7–4 J/cm2 and wavelengths of 600–700 nm are appropriate for light therapy. The results were dependent upon different parameters; therefore, optimization of parameters used in light therapy to obtain favorable results is required to provide more accurate comparison.