A Role for Photobiomodulation in the Prevention of Myocardial Ischemic Reperfusion Injury- A Systematic Review and Potential Molecular Mechanisms
Photobiomodulation in animal models showed consistently positive effects over a range of wavelengths and application parameters, with reductions in total infarct size (up to 76%), decreases in inflammation and scarring, and increases in tissue repair. Multiple molecular pathways were identified, including modulation of inflammatory cytokines, signalling molecules, transcription factors, enzymes and antioxidants.
OPEN FILEAmelioration of Cardiac Function and Activation of Anti-Inflammatory Vasoactive Peptides Expression in the Rat Myocardium by Low Level Laser Therapy
Our data suggest that LLLT diminishes the acute inflammation in the myocardium, reduces infarct size and attenuates left ventricle dysfunction post-MI and increases vasoactive peptides expression and nitric oxide (NO) generation.
OPEN FILEApplication of Low-Level Laser Therapy Following Coronary Artery Bypass Grafting Surgery
It is concluded that low-level laser irradiation after CABG surgery could decrease cardiac cellular damage and help accelerate the repair of cardiac tissue post-operatively. This may lower post-operative disability as well as bed rest period in these patients.
OPEN FILEHemodynamic Effect of Laser Therapy in Spontaneously Hypertensive Rats
LLLT promotes cellular and tissue photobiomodulation by means of changes in metabolism, leading to molecular, cellular and systemic changes.
OPEN FILELow Level Laser Application in the Early Myocardial Infarction Stage Has No Beneficial Role in Heart Failure
Low level laser therapy (LLLT) has been targeted as a promising approach that can mitigate post-infarction cardiac remodeling.
OPEN FILELow-level Laser Therapy Associated With High Intensity Resistance Training on Cardiac Autonomic Control of Heart Rate and Skeletal Muscle Remodeling in Wistar Rats
These results provide evidence for the positive benefits of LLLT and HIT with respect to enhanced muscle metabolic and cardiac autonomic function in Wistar rats.
OPEN FILELow-Level Laser Therapy to the Bone Marrow Reduces Scarring and Improves Heart Function Post-Acute Myocardial Infarction in the Pig
LLLT application to BM in the porcine model for MI caused a significant reduction in scarring, enhanced angiogenesis and functional improvement both in the acute and long term phase post-MI.
OPEN FILEThe effect of low-level laser therapy on oxidative stress and functional fitness in aged rats subjected to swimming an aerobic exercise
Laser therapy in conjunction with aerobic training may reduce oxidative stress, as well as increase VO2 (0.75)max, indicating that an aerobic exercise such as swimming increases speed and improves performance in aged animals treated with LLLT.
OPEN FILEThe hematologic effects of low intensity 650 nm laser irradiation on hypercholesterolemia rabbits
Conclusions: low energy laser improve microcirculation, rheological properties and blood lipid that might be related with erythrocytes aggregation and deformability.
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